The Wades were a generous couple until they lost the only person they loved, their 7 year old son, as times pass, they begin to face martial problems, that is until a blonde female stranger turns up at their house claiming that "They" are after her, then the mysterious stalkers break into the home that puts the three people to their limits.

In 1989, a breakthrough in advanced parasitic research on Cuttyhunk Island, gave scientists a jump in human evolution. Initial tests proved promising as subjects were experiencing heightened physical and mental strength and awareness. But, something in the experiment went horribly wrong and the island mysteriously lost three quarters of its population. Jamie Akerman fled the outbreak, which took her mothers life, twenty years ago. She now returns with her boyfriend and step brother, to sell the family property. There, they uncover the key to Jamie's disturbing past, and the horrifying secrets long suppressed by the town leader, Larkin. Now, a new strain of parasite has emerged, and threatens the island once again. Jamie struggles to survive and escape the obsessive pursuit of the local islanders who know that she has inherited more than she could ever have imagined.